Research Article
Icariin Attenuates Synaptic and Cognitive Deficits in an Aβ1–42-Induced Rat Model of Alzheimer’s Disease
Figure 5
Effect of ICA on PSD-95, BDNF, pTrkB, pCREB, and pAkt protein expressions in the hippocampi of Aβ1–42-infused rats. (a) Representative Western blot images showing PSD-95, BDNF, pTrkB/TrkB, pAkt/Akt, and pCREB/CREB expressions in the hippocampi of different groups. β-Actin was included as a loading control. (b, c, d, e, and f) PSD-95, BDNF, pTrkB/TrkB, pAkt/Akt, and pCREB/CREB expressions. The results are expressed as a percentage of the sham group. All data were analysed using one-way ANOVA and are presented as the mean ± SD. and versus the vehicle group. and versus the ICA-H group.
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