Research Article

Metabolic Disorders in HIV-Infected Adolescents Receiving Protease Inhibitors

Table 3

Prevalence of abnormal glucose metabolism, lipid metabolism, and metabolic syndrome features in HIV-infected adolescents receiving protease inhibitor- (PI-) based highly active antiretroviral therapy (HAART).

Diagnosis (%)

Abnormal glucose metabolism34 (42.5)
 (i) Prediabetes17 (22.1)
   IGT15 (19.5)
   IFG2 (2.6)
 (ii) Diabetes3 (3.8)
 (iii) Insulin resistance27 (33.8)
Abnormal lipid metabolism56 (70.0)
 (i) Hypertriglyceridemia35 (43.8)
 (ii) High LDL-cholesterol17 (21.3)
 (iii) Low HDL-cholesterol31 (38.8)
High blood pressure7 (8.8)
Metabolic syndrome8 (10.0)
 (i) Obesity plus 2 metabolic syndrome features6 (7.5)
 (ii) Obesity plus 3 metabolic syndrome features2 (2.5)
Metabolic syndrome features without obesity16 (20.0)
 (i) 2 metabolic syndrome features14 (17.5)
 (ii) 3 metabolic syndrome features2 (2.5)

IGT, impaired glucose tolerance; IFG, impaired fasting glucose.