Research Article

Jugular Venous Reflux Is Associated with Perihematomal Edema after Intracerebral Hemorrhage

Table 1

Baseline characteristics and risk factor profiles of patients with ICH.

JVR negativeJVR positivep value

Number of subjects, n3629NA
Age in years, mean (SD)52.9 (12.2)55.1 (9.3)0.422
Male gender, n (%)27 (75.0)24 (82.8)0.449
History of smoking, n (%)14 (38.9)13 (44.8)0.629
History of ICH, n (%)0 (0.0)4 (13.8)0.075
History of IS, n (%)4 (11.1)3 (10.3)NA
History of CAD, n (%)2 (5.6)2 (6.9)NA
History of hypertension, n (%)29 (80.6)26 (89.7)0.506
Irregular shape of hematoma, n (%)5 (13.9)9 (36%)0.095
Admission GCS, median (IQR)15 (13–15)14 (12–15)0.264
Admission mRS, median (IQR)4 (2–4)4 (2–5)0.308
Admission NIHSS, mean (SD)7.8 (5.1)8.4 (5.4)0.614
LDL (mmol/L), mean (SD)3.1 (0.9)2.8 (0.5)0.203
GLU (mmol/L), mean (SD)5.3 (1.4)5.0 (1.3)0.509
INR, mean (SD)1.00 (0.06)1.01 (0.04)0.214
First SBP (mmHg), mean (SD)171 (29)162 (24)0.184
First DBP (mmHg), mean (SD)99 (16)100 (15)0.771
Baseline hematoma volume (ml), mean (SD)19.52 (12.49)20.29 (10.85)0.794
sIVH, n (%)6 (16.7)5 (17.2)1.000
Hematoma location in basal ganglia or thalamus, n (%)31 (86.1)26 (90.0)0.958
Intraluminal structural abnormality, n (%)2 (5.6)5 (17.2)0.268
 Malformed valve2 (5.6)5 (17.2)
 Flap00
 Web00
 Membrane00
 Septum00
Extraluminal structural abnormality, n (%)00

NA, not applicable; ICH, intracerebral hemorrhage; IS, ischemic stroke; CAD, coronary artery disease; GCS, Glasgow Coma Scale; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; LDL, low density lipoprotein; GLU, blood glucose; INR, international normalized ratio; SBP, systolic blood pressure; DBP, diastolic blood pressure; sIVH, secondary intraventricular hemorrhage; IQR, interquartile range; SD, standard deviation; first blood pressure measured after symptom observation.