Cranioencephalic trauma High age Low GCS Pupillary changes/anisocoria/nonreactive bilateral mydriasis Alteration or absence of ocular movement Injuries according to the Marshall CT classification (IV and VI) Type and gravity of injury according to CT. Presence of traumatic SAH Intracranial hypertension Hypoxia/hypotension and presence of secondary injury Necessity of intubation Coagulopathy/previous anticoagulant treatment/necessity of blood transfusion Associated spinal cord injury SAH Age Neurologic function High score in Hunt and Hess scale High score in WFNS scale Fisher scale. Blood volume and location High score in Ogilvy and Carter scale Size and localization of aneurism/hemorrhage recurrence Hyperglycemia Ischemic and hemorrhagic brain stroke High score in NIHSS and iScore High ICH score Low GCS Volume of hematoma that varies depending on location: (i) Basal ganglia hemorrhage ≥ 60 cc, mortality 100% (ii) Lobar hemorrhage ≥ 60 cc, mortality 71% (iii) Posterior fossa lethal hemorrhage: Cerebellar location > 30 cc Pontine location 5 cc Diabetes/hyperglycemia on admission Previous antiaggregation/anticoagulation Auricular fibrillation