BioMed Research International

Research Article

MET18 Deficiency Increases the Sensitivity of Yeast to Oxidative Stress and Shortens Replicative Lifespan by Inhibiting Catalase Activity

Table 1

Yeast strains in this study.
Strain nameGenotypeCommentsSource
BY4743MATa/MATαhis3Δ1/his3Δ1 leu2Δ0/leu2Δ0 lys2/lys2Δ0 met15Δ0/met15 ura3Δ0/ura3Δ0Wild-type strainGift from Matt Kaeberlein
GDMUB1001BY4743 MET18::URA3Deletion of one copy of MET18 in BY4743This experiment
GDMUB1002BY4743 + pAUR123BY4743 harboring pAUR123This experiment
GDMUB1003BY4743MET18::URA3 + pAUR123GDMUB1001 harboring pAUR123This experiment
GDMUB1004BY4743MET18::URA3 + pAUR123-CTA1GDMUB1001 harboring pAUR123-CTA1This experiment
GDMUB1005BY4743MET18::URA3 + pAUR123-CTT1GDMUB1001 harboring pAUR123-CTT1This experiment