Research Article

Maternal Prepregnancy BMI and Glucose Level at 24–28 Gestational Weeks on Offspring’s Overweight Status within 3 Years of Age

Table 1

Characteristics of 21,354 mother-infant pairs according to different categories of maternal prepregnancy body mass index and glucose level at 24–28 gestational weeks.

Prepregnancy body mass index (kg/m2) valueGlucose level (mmol/L) value
<18.518.5–23.924.0–27.9≥28<7.8≥7.8

Number of subjects2,39413,6024,0551,30317,3214,033
Maternal characteristics
Maternal age, y27.1 (2.7)27.9 (2.9)28.2 (3.0)28.3 (3.2)<0.00127.8 (2.9)28.5 (3.1)<0.001
Ethnicity (Han), %95.995.895.796.00.9895.796.30.079
Mother’s education, %<0.0010.97
 ≤12 years25.823.128.639.525.525.5
 >12 years74.276.971.460.574.574.6
Smoking during pregnancy, %2.132.022.152.760.362.171.810.15
History of abortion, %30.330.734.436.8<0.00131.134.5<0.001
Prepregnancy body mass index, kg/m217.6 (0.8)21.1 (1.5)25.6 (1.1)30.5 (2.4)<0.00121.9 (3.3)23.2 (3.7)<0.001
Systolic blood pressure at 24–28 gestational weeks, mmHg103 (10)107 (10)111 (10)115 (11)<0.001107 (10)109 (11)<0.001
Glucose level at 24–28 gestational weeks, mmol/L6.25 (1.3)6.50 (1.5)6.92 (1.6)7.27 (1.8)<0.0016.05 (1.0)8.95 (1.2)<0.001
Child characteristics
Gestational age at delivery, weeks39.6 (1.4)39.6 (1.4)39.6 (1.6)39.4 (1.7)<0.00139.6 (1.4)39.4 (1.6)<0.001
Boy, %49.552.051.650.60.1451.651.50.95
Mode of infant feeding, %<0.0010.43
 Exclusive breast-feeding16.016.214.912.215.715.5
 Mixed breast and formula36.735.438.441.636.437.0
 Weaned from breast-feeding45.346.243.742.945.644.8
 Exclusive formula feeding2.12.13.03.32.32.7

Data are means (SD) or percentage.