Maternal Prepregnancy BMI and Glucose Level at 24–28 Gestational Weeks on Offspring’s Overweight Status within 3 Years of Age

Table 4

Odds ratio and 95% confidence interval of macrosomia at birth or overweight/obesity during early life according to different categories of glucose level stratified by prepregnancy BMI.

	Glucose level (mmol/L)		Glucose level as a continuous variable (1-unit increase)
	<7.8	≥7.8
Prepregnancy BMI < 24 kg/m^2
Number of subjects	13,395	2,601	15,996
Macrosomia at birth	1.00	1.31 (1.14–1.51)	1.15 (1.11–1.19)
Overweight/obesity at 12th month	1.00	1.12 (1.01–1.24)	1.02 (1.00–1.05)
Overweight/obesity at 24th month	1.00	0.95 (0.85–1.07)	1.00 (0.97–1.03)
Overweight/obesity at 36th month	1.00	1.14 (1.01–1.29)	1.02 (0.99–1.06)
Prepregnancy BMI ≥ 24 kg/m^2
Number of subjects	3,926	1,432	5,358
Macrosomia at birth	1.00	1.36 (1.16–1.61)	1.16 (1.11–1.21)
Overweight/obesity at 12th month	1.00	0.99 (0.86–1.14)	0.99 (0.96–1.03)
Overweight/obesity at 24th month	1.00	0.92 (0.79–1.07)	0.99 (0.95–1.03)
Overweight/obesity at 36th month	1.00	1.03 (0.88–1.20)	0.99 (0.95–1.03)

Adjusted for maternal age, ethnicity, education, smoking status, history of abortion, systolic blood pressure at 24–28 gestational weeks, gestational age at delivery, and child sex in macrosomia analyses and additionally for birthweight and mode of infant feeding in childhood overweight/obesity analyses.