Research Article

Vitamin D Modulates Hematological Parameters and Cell Migration into Peritoneal and Pulmonary Cavities in Alloxan-Diabetic Mice

Table 1

Quantification of pulmonary and peritoneal leukocytes.

White cells (105 cells/mL)
SiteGroupTotalMacrophageLymphocyteNeutrophil

PeritoneumControl911.2 ± 2.88.1 ± 2.32.95 ± 0.00.1 ± 0.0
Vitamin D716.0 ± 3.212.0 ± 2.23.4 ± 1.5
Diabetic718.7 ± 3.014.8 ± 3.23.6 ± 0.80.2 ± 0.1
Diabetic + vitamin D77.6 ± 1.71.0 ± 0.50.3 ± 0.2
LungControl34.6 ± 2.03.5 ± 1.90.9 ± 0.60.2 ± 0.1
Vitamin D49.1 ± 4.06.8 ± 2.42.0 ± 1.50.3 ± 0.2
Diabetic314.5 ± 4.011.5 ± 2.12.5 ± 1.40.9 ± 0.6
Diabetic + vitamin D319.9 ± 0.50.1 ± 0.10.1 ± 0.0

Mice were rendered diabetic by the injection of alloxan (60 mg/kg, i.v.), 10 days before vitamin D supplementation (800 IU/day, o.v.). BAL and PeL were performed 24 h thereafter. Values are expressed as means ± SD.
versus corresponding values in control group.
versus corresponding values in diabetic group.