Research Article
PinX1 Is a Potential Prognostic Factor for Non-Small-Cell Lung Cancer and Inhibits Cell Proliferation and Migration
Table 2
Univariate analysis with regard to DFS and OS.
| | DFS | OS | value | HR | 95% CI | value | HR | 95% CI |
| Sex (male, female) | 0.008 | 1.836 | 1.175–2.871 | 0.008 | 1.827 | 1.169–2.854 | Age (<60 years, ≥61 years) | 0.629 | 1.115 | 0.716–1.738 | 0.463 | 1.181 | 0.758–1.840 | Smoking status (no, yes) | 0.029 | 0.604 | 0.385–0.949 | 0.021 | 0.588 | 0.375–0.923 | Histology (squamous, adenocarcinoma) | 0.617 | 0.887 | 0.554–1.420 | 0.526 | 0.859 | 0.536–1.375 | Surgical procedure (pneumonectomy, lobectomy, other) | 0.196 | 1.297 | 0.874–1.924 | 0.109 | 1.379 | 0.931–2.403 | Lesion (peripheral, central) | 0.079 | 0.661 | 0.417–1.048 | 0.063 | 0.646 | 0.408–1.023 | Tumour location (left, right) | 0.466 | 0.848 | 0.545–1.320 | 0.431 | 0837 | 0.538–1.303 | N0/N1-2 | 0.000 | 3.605 | 2.166–6.001 | 0.000 | 3.376 | 2.030–5.612 | Subcarinal lymph node metastasis (positive, negative) | 0.000 | 4.035 | 2.528–6.443 | 0.000 | 3.586 | 2.247–5.721 | Pathological stage (I, II, IIIA) | 0.000 | 1.710 | 1.417–2.065 | 0.000 | 1.673 | 1.387–2.018 | PinX1 (positive, negative) | 0.019 | 2.003 | 1.122–3.573 | 0.021 | 1.976 | 1.107–3.528 |
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DFS, disease-free survival; OS, overall survival; HR, hazard ratio; CI, confidence interval.
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