PinX1 Is a Potential Prognostic Factor for Non-Small-Cell Lung Cancer and Inhibits Cell Proliferation and Migration

Table 2

Univariate analysis with regard to DFS and OS.

	DFS			OS
	value	HR	95% CI	value	HR	95% CI
Sex (male, female)	0.008	1.836	1.175–2.871	0.008	1.827	1.169–2.854
Age (<60 years, ≥61 years)	0.629	1.115	0.716–1.738	0.463	1.181	0.758–1.840
Smoking status (no, yes)	0.029	0.604	0.385–0.949	0.021	0.588	0.375–0.923
Histology (squamous, adenocarcinoma)	0.617	0.887	0.554–1.420	0.526	0.859	0.536–1.375
Surgical procedure (pneumonectomy, lobectomy, other)	0.196	1.297	0.874–1.924	0.109	1.379	0.931–2.403
Lesion (peripheral, central)	0.079	0.661	0.417–1.048	0.063	0.646	0.408–1.023
Tumour location (left, right)	0.466	0.848	0.545–1.320	0.431	0837	0.538–1.303
N0/N1-2	0.000	3.605	2.166–6.001	0.000	3.376	2.030–5.612
Subcarinal lymph node metastasis (positive, negative)	0.000	4.035	2.528–6.443	0.000	3.586	2.247–5.721
Pathological stage (I, II, IIIA)	0.000	1.710	1.417–2.065	0.000	1.673	1.387–2.018
PinX1 (positive, negative)	0.019	2.003	1.122–3.573	0.021	1.976	1.107–3.528

DFS, disease-free survival; OS, overall survival; HR, hazard ratio; CI, confidence interval.