Review Article

Cooccurrences of Putative Endogenous Retrovirus-Associated Diseases

Table 1

Cooccurrence of diseases with possible involvement of ERV reactivation.

Number of casesAssociation between diseasesCommentsRef.

MS and schizophrenia
1n.a.Case report[80]
2n.a.Case report[81]
10n.a.Research study[82]
1n.a.Case report[83]
n.a.PositiveEpidemiological investigation[84]
3No associationPopulation-based register study[85]
1n.a.Case report[86]
67PositivePopulation-based controlled study[87]
63PositivePopulation-based register study[88]
39No associationEpidemiologic investigation[89]
36NegativePopulation-based register study[90]

MS and T1D
5PositivePopulation-based register study[91]
3n.a.Clinical register study[92]
1No associationClinical register study[93]
28PositiveCohort study[94]
n.a.PositiveClinical register study[95]
11PositivePopulation-based cohort study[96]

MS and ALS
1n.a.Case report[97]
1n.a.Case report[98]
1n.a.Case report[99]
1n.a.Case report[100]
1n.a.Case report[101]
1n.a.Case report[102]
1n.a.Research study[103]
1n.a.Case report[104]
1n.a.Case report[105]
7PositiveEpidemiologic investigation[106]
143PositiveClinical register study[107]
1No associationPopulation-based case-control study[108]

MS and HIV infection
1n.a.Case report[109]
1n.a.Case report[110]
1No associationPopulation-based register study[111]
1n.a.Case report[112]
10NegativeComparative cohort study[113]
1n.a.Case report[114]
1n.a.Case report[115]

Schizophrenia and T1D
0NegativePopulation-based register study[116]
n.a.No associationPopulation-based register study[117]
24No associationPopulation-based register study[85]
24NegativePopulation-based register study[118]

Schizophrenia and ALS
2n.a.Case report[119]
1n.a.Case report[120]
2n.a.Case report[121]
1n.a.Case report[122]
1n.a.Case report[123]
2n.a.Case report[124]
2n.a.Case report[125]
2n.a.Case report[126]

Schizophrenia and HIV infection
13n.a.Clinical register study[127]
3n.a.Clinical cohort[128]
8n.a.Cohort study[129]
11n.a.Clinical cohort[130]
10n.a.Clinical cohort[131]
13n.a.Clinical cohort[132]
1n.a.Clinical cohort[133]
476n.a.Population-based register study[134]
7n.a.Clinical cohort[135]
11n.a.Clinical cohort[136]
1n.a.Case report[137]
28n.a.No data[138]
68PositivePopulation-based cohort study[139]

T1D and ALS
216PositiveClinical register study[107]
43No associationPopulation-based case-control study[140]

T1D and HIV infection
1n.a.Case report[141]
1n.a.Case report[142]
1n.a.Case report[143]
1n.a.Case report[144]
1n.a.Case report[145]
1n.a.Case report[146]
1n.a.Case report[147]
1n.a.Case report[148]
7n.a.Clinical register study[149]
3n.a.Case report[150]
10n.a.Population-based register study[151]
1n.a.Case report[152]

ALS and HIV infection
1n.a.Case report[153]
1n.a.Case report[154]
1n.a.Retrospective hospital cohorts[155]
1n.a.Case report[156]
2n.a.Case report[157]

Not available, not tested, or not presented in the publication.
The number of cases was not reported; the prevalence of psychotic disorders among more than 10,000 MS patients was reported as 1.3%.
The number of cases was inferred from incidence as presented in the publication; the number was not explicitly reported.
Not available; the number of patients was not reported.
No schizophrenia cases were found among 1,154 diabetics below 27 years of age.
Not available; the number of cases was not reported; the prevalence of psychoses among nearly 17,000 patients with T1D was reported as 0.8%.
Number of HIV positive patients developing schizophrenia.