Diagnostic and Therapeutic Biomarkers in Glioblastoma: Current Status and Future Perspectives

Figure 1

Glioblastoma characterization. (a) Axial contrast-enhanced T1-weighted MR image shows a large enhancing mass in the left temporal lobe in a 54-year-old woman diagnosed with GBM. (b, c) GBM formalin-fixed paraffin-embedded sections stained for H&E and EGFRvIII. (d) Frequent alterations in critical signaling pathways found in GBM.