Basal and Activated Calcium Sensitization Mediated by RhoA/Rho Kinase Pathway in Rats with Genetic and Salt Hypertension

Table 2

Initial values of mean arterial pressure (MAP, mmHg) and MAP changes induced by nifedipine and additional fasudil as well as MAP levels reached after inhibitors administration in WKY and SHR rats and HanSD and TGR animals as well as in SS/Jr or SR/Jr Dahl rats fed either LS or HS diet (Experiment ).

Strain	Number of rats	Initial MAP	Delta MAP nifedipine	MAP after nifedipine	Delta MAP additive fasudil	MAP after nifedipine + fasudil
SHR	12
WKY	9
TGR	11
HanSD	12
SS/Jr-HS	10
SS/Jr-LS	6
SR/Jr-HS	8
SR/Jr-LS	8

Data are means ± SEM. Significantly different ()from the respective normotensive controls and ^#from the corresponding rat strain fed a low-salt diet.