In Vitro Evaluations and In Vivo Toxicity and Efficacy Studies of MFM501 against MRSA

Table 5

Survival rates of control and MRSA-infected mice after being treated with MFM501.

Mice groups	Treated/untreated mice	Total of mice surviving	% survive
Control; mice	Untreated—MRSA adjuvant only; (−ve control)	0/8	0
	MRSA adjuvant + 25 mg/kg linezolid (+ve control #1)	8/8	100
	MHB + 5% mucin only; (+ve control #2)	8/8	100
	Healthy and untreated mice; (+ve control #3)	8/8	100
Mice treated with MFM501	125 mg/kg	5/8	62.5
	62.5 mg/kg	3/8	37.5
	31.3 mg/kg	2/8	25
	15.6 mg/kg	2/8	25