Potential Anticancer Mechanisms of a Novel EGFR/DNA-Targeting Combi-Molecule (JDF12) against DU145 Prostate Cancer Cells: An iTRAQ-Based Proteomic Analysis

Figure 2

The effects of JDF12 on the cell apoptosis. Early apoptosis cells were Annexin V+/PI−, and later apoptosis cells were Annexin V+/PI+. (a) 0 h; (b) 24 h; (c) 48 h; (d) the overall apoptosis rate was significant increased after treatment of IC₅₀ JDF12 for 24 h and 48 h. Results were presented as mean ± SD from three independent experiments. , .

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