Research Article
Pharmacokinetic Properties of Adenosine Amine Congener in Cochlear Perilymph after Systemic Administration
Table 3
Accuracy and precision assessment. (a) Plasma samples (
); (b) homogenised cochlear tissue samples (
); (c) perilymph samples (
).
| (a) |
| | Spiked concentration (µg/mL) | Mean concentration (µg/mL) | Accuracy (%) | Precision (RSD, %) |
| | 1.67 | 1.56 | 93.41 | 5.53 | | 16.67 | 15.22 | 91.30 | 12.51 |
|
|
| (b) |
| | Spiked concentration (ng/mL) | Mean concentration (ng/mL) | Accuracy (%) | Precision (RSD, %) |
| | 1 | 0.88 | 88 | 8.36 | | 50 | 43.29 | 86.58 | 11.95 |
|
|
| (c) |
| | Spiked concentration (ng/mL) | Mean concentration (ng/mL) | Accuracy (%) | Precision (RSD, %) |
| | 1 | 0.91 | 91 | 10.22 | | 50 | 44.76 | 89.52 | 9.64 |
|
|
