DNA Damage as a Driver for Growth Delay: Chromosome Instability Syndromes with Intrauterine Growth Retardation

Figure 4

Fanconi anemia patient. This six-year-old girl is 105 cm tall; her height is just below the 5th percentile, and her at-term birth weight is reported to be of 1900 gr. Characteristic features of FA are evident: skin hyperpigmentation, bilateral radial defects consisting of bilateral thenar hypoplasia, and absent fold of the right thumb which cannot be bent.