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BioMed Research International
Volume 2017, Article ID 8206281, 7 pages
https://doi.org/10.1155/2017/8206281
Research Article

The Protective Effect of Chrysanthemum indicum Extract against Ankylosing Spondylitis in Mouse Models

1Infectious Immune Department of Rheumatism, Tianjin Hospital, Jiefangnan Road 406, Tianjin 300211, China
2Department of Rehabilitation Medicine, Tianjin Medical University, Tianjin 300052, China
3Department of Botany and Microbiology, Addiriyah Chair for Environmental Studies, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia

Correspondence should be addressed to Dongsheng Yu; moc.621@mdgnehsgnoduy

Received 12 December 2016; Accepted 15 January 2017; Published 2 February 2017

Academic Editor: Nigora Mukhamedova

Copyright © 2017 Mei Dong et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Y.-F. Liu, H. Dong, S.-H. Tu, C.-H. Zheng, P.-L. Liu, and Y.-H. Hu, “Etanercept in the treatment of ankylosing spondylitis: a systematic review and meta-analysis,” Experimental and Therapeutic Medicine, vol. 8, no. 5, pp. 1585–1592, 2014. View at Publisher · View at Google Scholar · View at Scopus
  2. R. A. Colbert, T. M. Tran, and G. Layh-Schmitt, “HLA-B27 misfolding and ankylosing spondylitis,” Molecular Immunology, vol. 57, no. 1, pp. 44–51, 2014. View at Publisher · View at Google Scholar · View at Scopus
  3. L. E. Dean, G. T. Jones, A. G. Macdonald, C. Downham, R. D. Sturrock, and G. J. Macfarlane, “Global prevalence of ankylosing spondylitis,” Rheumatology, vol. 53, no. 4, pp. 650–657, 2014. View at Publisher · View at Google Scholar · View at Scopus
  4. C.-T. Chou, A.-P. Huo, H.-N. Chang, C.-Y. Tsai, W.-S. Chen, and H.-P. Wang, “Cytokine production from peripheral blood mononuclear cells in patients with ankylosing spondylitis and their first-degree relatives,” Archives of Medical Research, vol. 38, no. 2, pp. 190–195, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. D. van der Heijde, R. Landewé, X. Baraliakos et al., “Radiographic findings following two years of infliximab therapy in patients with ankylosing spondylitis,” Arthritis & Rheumatism, vol. 58, no. 10, pp. 3063–3070, 2008. View at Publisher · View at Google Scholar · View at Scopus
  6. D. van der Heijde, D. Salonen, B. N. Weissman et al., “Assessment of radiographic progression in the spines of patients with ankylosing spondylitis treated with adalimumab for up to 2 years,” Arthritis Research & Therapy, vol. 11, no. 4, article R127, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. P. C. Robinson and M. A. Brown, “Genetics of ankylosing spondylitis,” Molecular Immunology, vol. 57, no. 1, pp. 2–11, 2014. View at Publisher · View at Google Scholar · View at Scopus
  8. Y. Morita, J. Yang, R. Gupta et al., “Dendritic cells genetically engineered to express IL-4 inhibit murine collagen-induced arthritis,” The Journal of Clinical Investigation, vol. 107, no. 10, pp. 1275–1284, 2001. View at Publisher · View at Google Scholar · View at Scopus
  9. K. Okano, K. Kimura, Y. Tanaka, K. Tsuchiya, and T. Akiba, “Direct measurement of reactive oxygen species in leukocytes during hemodialysis therapy,” International Journal of Clinical and Experimental Medicine, vol. 8, no. 11, pp. 20959–20964, 2015. View at Google Scholar · View at Scopus
  10. L. D. Kozaci, I. Sari, A. Alacacioglu, S. Akar, and N. Akkoc, “Evaluation of inflammation and oxidative stress in ankylosing spondylitis: a role for macrophage migration inhibitory factor,” Modern Rheumatology, vol. 20, no. 1, pp. 34–39, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. H. Matsuda, T. Morikawa, I. Toguchida, S. Harima, and M. Yoshikawa, “Medicinal flowers. VI. Absolute stereostructures of two new flavanone glycosides and a phenylbutanoid glycoside from the flowers of Chrysanthemum indicum L.: their inhibitory activities for rat lens aldose reductase,” Chemical & Pharmaceutical Bulletin, vol. 50, no. 7, pp. 972–975, 2002. View at Publisher · View at Google Scholar · View at Scopus
  12. T. Kato, K. Noguchi, Y. Miyamoto et al., “Effects of Chrysanthemum indicum Linn. on coronary, vertebral, renal and aortic blood flows of the anesthetized dog,” Archives Internationales De Pharmacodynamie Et De Therapie, vol. 285, no. 2, pp. 288–300, 1987. View at Google Scholar
  13. W. M. Cheng, J. Li, T. You, and C. Hu, “Anti-inflammatory and immunomodulatory activities of the extracts from the inflorescence of Chrysanthemum indicum Linné,” Journal of Ethnopharmacology, vol. 101, no. 1–3, pp. 334–337, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. S. Y. Zhu, Y. Yang, H. Yu, Y. Ying, and G. Zou, “Chemical composition and antimicrobial activity of the essential oils of Chrysanthemum indicum,” Journal of Ethnopharmacology, vol. 96, no. 1-2, pp. 151–158, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. M. Yoshikawa, T. Morikawa, I. Toguchida, S. Harima, and H. Matsuda, “Medicinal flowers. II. Inhibitors of nitric oxide production and absolute stereostructures of five new germacrane-type sesquiterpenes, kikkanols D, D monoacetate, E, F, and F monoacetate from the flowers of Chrysanthemum indicum L.,” Chemical & Pharmaceutical Bulletin, vol. 48, no. 5, pp. 651–656, 2000. View at Publisher · View at Google Scholar · View at Scopus
  16. W. Ren, J. Duan, J. Yin et al., “Dietary l-glutamine supplementation modulates microbial community and activates innate immunity in the mouse intestine,” Amino Acids, vol. 46, no. 10, pp. 2403–2413, 2014. View at Publisher · View at Google Scholar · View at Scopus
  17. K. R. Haynes, A. R. Pettit, R. Duan et al., “Excessive bone formation in a mouse model of ankylosing spondylitis is associated with decreases in Wnt pathway inhibitors,” Arthritis Research and Therapy, vol. 14, no. 6, 2012. View at Publisher · View at Google Scholar · View at Scopus
  18. R. J. U. Lories, I. Derese, and F. P. Luyten, “Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis,” The Journal of Clinical Investigation, vol. 115, no. 6, pp. 1571–1579, 2005. View at Publisher · View at Google Scholar · View at Scopus
  19. T. Bárdos, Z. Szabó, M. Czipri et al., “A longitudinal study on an autoimmune murine model of ankylosing spondylitis,” Annals of the Rheumatic Diseases, vol. 64, no. 7, pp. 981–987, 2005. View at Publisher · View at Google Scholar · View at Scopus
  20. M.-Y. Shiau, M.-K. Lo, C.-P. Chang, T.-P. Yang, K.-T. Ho, and Y.-H. Chang, “Association of tumour necrosis factor α promoter polymorphisms with ankylosing spondylitis in Taiwan,” Annals of the Rheumatic Diseases, vol. 66, no. 4, pp. 562–563, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. X. Gu, H. Wu, and P. Fu, “Allicin attenuates inflammation and suppresses HLA-B27 protein expression in ankylosing spondylitis mice,” BioMed Research International, vol. 2013, Article ID 171573, 6 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  22. M. Feijóo, I. Túnez, I. Tasset, P. Montilla, A. Ruiz, and E. Collantes, “Infliximab reduces oxidative stress in ankylosing spondylitis,” Clinical and Experimental Rheumatology, vol. 27, no. 1, pp. 167–168, 2009. View at Google Scholar
  23. M. Karakoc, O. Altindag, H. Keles, N. Soran, and S. Selek, “Serum oxidative-antioxidative status in patients with ankylosing spondilitis,” Rheumatology International, vol. 27, no. 12, pp. 1131–1134, 2007. View at Publisher · View at Google Scholar · View at Scopus
  24. I.-S. Kim, H.-M. Ko, S. Koppula, B.-W. Kim, and D.-K. Choi, “Protective effect of Chrysanthemum indicum Linne against 1-methyl-4-phenylpridinium ion and lipopolysaccharide-induced cytotoxicity in cellular model of Parkinson's disease,” Food and Chemical Toxicology, vol. 49, no. 4, pp. 963–973, 2011. View at Publisher · View at Google Scholar · View at Scopus
  25. U. Lange, J. Teichmann, and H. Stracke, “Correlation between plasma TNF-alpha, IGF-1, biochemical markers of bone metabolism, markers of inflammation/disease activity, and clinical manifestations in ankylosing spondylitis,” European Journal of Medical Research, vol. 5, no. 12, pp. 507–511, 2000. View at Google Scholar · View at Scopus
  26. M. Schulz, H. Dotzlaw, and G. Neeck, “Ankylosing spondylitis and rheumatoid arthritis: serum levels of TNF-α and its soluble receptors during the course of therapy with etanercept and infliximab,” BioMed Research International, vol. 2014, Article ID 675108, 7 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  27. C. Liu, T. Hong, M. Shao, Z. Chen, and C. Wang, “Melatonin synergized with cyclosporine a improves cardiac allograft survival by suppressing inflammation and apoptosis,” Molecular Medicine Reports, vol. 10, no. 3, pp. 1323–1328, 2014. View at Publisher · View at Google Scholar · View at Scopus
  28. T. W. Kim, Y. J. Kim, S. R. Park et al., “Erratum to ‘Chrysanthemum indicum attenuates cisplatin-induced nephrotoxicity both in vivo and in vitro (vol. 10, pp. 397, 2015)’,” Natural Product Communications, vol. 10, no. 7, article 1331, 2015. View at Google Scholar
  29. S. C. Kang, S. Y. Lim, and Y.-J. Song, “Lupeol is one of active components in the extract of Chrysanthemum indicum Linne that inhibits LMP1-induced NF-κB activation,” PLoS ONE, vol. 8, no. 11, Article ID e82688, 2013. View at Publisher · View at Google Scholar · View at Scopus
  30. M. S. Cheon, T. Yoon, D. Y. Lee et al., “Chrysanthemum indicum Linné extract inhibits the inflammatory response by suppressing NF-κB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages,” Journal of Ethnopharmacology, vol. 122, no. 3, pp. 473–477, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. H. Appel, G. Ruiz-Heiland, J. Listing et al., “Altered skeletal expression of sclerostin and its link to radiographic progression in ankylosing spondylitis,” Arthritis & Rheumatism, vol. 60, no. 11, pp. 3257–3262, 2009. View at Publisher · View at Google Scholar · View at Scopus
  32. R. Baron and G. Rawadi, “Targeting the Wnt/β-catenin pathway to regulate bone formation in the adult skeleton,” Endocrinology, vol. 148, no. 6, pp. 2635–2643, 2007. View at Publisher · View at Google Scholar · View at Scopus
  33. S. Uderhardt, D. Diarra, J. Katzenbeisser et al., “Blockade of Dickkopf (DKK)-1 induces fusion of sacroiliac joints,” Annals of the Rheumatic Diseases, vol. 69, no. 3, pp. 592–597, 2010. View at Publisher · View at Google Scholar · View at Scopus