Ameliorative Effect of Cactus (Opuntia ficus indica) Extract on Lithium-Induced Nephrocardiotoxicity: A Biochemical and Histopathological Study

Figure 3

Light micrographs of hematoxylin-eosin (H&E) stained kidney paraffin sections (×400): (a) control group showing normal histological structures; (b) lithium-treated group showing necrosis of renal cells (), severe degenerative changes in tubules, and damaged glomeruli; (c) the normal kidney structure of rats treated with CCE; (d) O. ficus indica cladodes extract with lithium group showing marked improvement in the histological picture with minimal tubules damage and normal structure of the glomeruli.

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