Clinical Study

Chronic Kidney Dysfunction Can Increase the Risk of Deep Vein Thrombosis after Total Hip and Knee Arthroplasty

Table 1

Characteristic data of the subjects.

VariablesTotal patientsTotal patients
Without DVT
( = 1030)
With DVT
( = 244)
valueWithout symptomatic DVT
( = 1210)
With symptomatic DVT
( = 64)
value

Age (mean years ± SD)64.4 ± 13.168.9 ± 10.1<0.00165.0 ± 12.867.9 ± 11.90.083
Female gender686 (66.6%)184 (82.1%)0.007820 (67.8)50 (78.1%)0.083
BMI (mean kg/m2  ± SD)24.6 ± 4.225.0 ± 4.40.13824.6 ± 4.326.0 ± 3.80.012
Hypertension420 (40.9%)107 (43.9%)0.380501 (41.4%)26 (40.6%)0.092
Insulin resistance135 (13.0%)27 (11.1%)0.389154 (12.7%)8 (12.5%)0.988
Smoking history64 (6.2%)14 (5.7%)0.78076 (6.3%)2 (3.1%)0.305
Malignancy20 (2.0%)10 (4.1%)0.04626 (2.1%)4 (6.2%)0.035
Heart disease104 (10.3%)26 (10.7%)0.079119 (9.8%)11 (17.2%)0.058
Thrombosis history129 (12.5%)38 (15.6%)0.206148 (12.2%)19 (29.7%)<0.001
eGFR (mean ml/min per 1.73 m2  ± SD)148.1 ± 54.0129.6 ± 40.9<0.001146.0 ± 52.5116.5 ± 38.4<0.001
D-dimer (mg/L)1.3 ± 3.61.1 ± 2.20.5901.2 ± 3.51.2 ± 2.00.970
CRP4.9 ± 1.25.6 ± 0.90.0735.1 ± 1.35.4 ± 1.00.154
Fibrinogen (g/L)3.3 ± 0.83.2 ± 0.80.4563.3 ± 0.83.3 ± 0.70.711

< 0.05 was considered statistically significant.
TJA, total joint arthroplasty; DVT, deep vein thrombosis; SD, standard deviation; BMI, body mass index; eGFR, estimated glomerular filtration rate; CRP, C-reactive protein.