BioMed Research International / 2017 / Article / Tab 2

Research Article

Role of P-Glycoprotein Inhibitors in the Bioavailability Enhancement of Solid Dispersion of Darunavir

Table 2

Comparative dissolution profile of nine batches of SD prepared using polymer P1 (Soluplus) and P2 (Kolliphor TPGS) in acetate buffer pH 4.5. Data presented as mean ± SD, for each formulation.

Formulation codePolymerCumulative % drug release (±SD)
 After 30 min After 60 min  After 90 min

SD1P1
SD2P1
SD3P2
SD4P2
SD5P1
SD6P2
SD7P2
SD8P1
SD9P1
SD10P2
SD11P2
SD12P1
SD13P2
SD14P1
SD15P2
SD16P2
SD17P1
SD18P1

P1 = Soluplus; P2 = Kolliphor TPGS.

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