Plant Proteinase Inhibitor BbCI Modulates Lung Inflammatory Responses and Mechanic and Remodeling Alterations Induced by Elastase in Mice

Figure 4

(a) Mean and SE of BAL total cells of all experimental groups. The elastase-induced group had a greater total number of cells than the control groups . The treatment with BbCI (ELABC) attenuated this increase compared with ELA group . (b) Mean and SE of the macrophage counts in the BAL of all animals. Animals that received elastase (ELA and ELABC) had greater values than SAL and SALBC groups . There were no differences between the ELA and ELABC groups. (c) Mean and SE of neutrophil counts from the BAL samples of all experimental groups. The elastase-induced group (ELA) had greater values than the control groups . The treatment with proteinase inhibitor (ELABC) attenuated this increase . (d) Mean and SE of the lymphocyte counts in the BAL of all animals. The elastase-induced groups (ELA and ELABC) had greater values than the control groups SAL and SALBC . There were no differences between the ELA and ELABC groups.

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