Simvastatin Ameliorates PAK4 Inhibitor-Induced Gut and Lung Injury

Figure 1

Effect of the PAK4 inhibitor and simvastatin on lung tissues. The alveolar wall was thickened, and wet-to-dry (W/D) values were increased after administration of the PAK4 inhibitor; meanwhile, simvastatin alleviated these effects. < 0.05 versus control rats; < 0.05 versus P + S treated rats.