Research Article
The Prevalence and Replication Capacity of a Tibetan Dominant HBV Strain, C/D Recombinant
Table 1
Distribution of HBV genotypes in enrolled Han patients and Tibetan patients.
| | Items | Statistical description percentage (amount)/median (interquartile range) | Statistical value | value | | Han patients () | Tibetan patients () |
| | Genotype | B 65.92% ()
C 30.57% ()
B/C 2.55% ()
C/D 0.96% () | B 17.65% ()
C 5.88% ()
D 41.18% ()
C/D 35.29% () | Fisher | <0.001 | | Gender | Male 84.08% ()
Female 15.92% () | Male 82.35% ()
Female 17.65% () | | 1 | | Age | 33.5 (15) | 38 (22.5) | | 0.308 | | Alcohol | Alcohol-abuse 18.47% ()
Alcohol-free 81.53% () | Alcohol-abuse 35.29% ()
Alcohol-free 64.71% () | | 0.1629 | | Family history | Positive 39.17% ()
Negative 60.83% () | Positive 58.82% ()
Negative 41.18% () | | 0.1752 | | ALT (IU/L) | 40 (41) | 38 (34.5) | | 0.388 | | TB (umol/L) | 12.50 (9.44) | 12.82 (6.76) | | 0.596 | | ALB (g/L) | 50.70 (23.60) | 47.50 (8.20) | | 0.104 | | ALP (IU/L) | 91.50 (42) | 93 (34) | | 0.831 | | GGT (IU/L) | 49 (50) | 45 (41) | | 0.629 | | AFP (ng/mL) | 3.46 (4.25) | 3.06 (5.02) | | 0.705 | | HBeAg | Positive 66.56% ()
Negative 33.44% () | Positive 76.47% ()
Negative 23.53% () | | 0.5606 | | log10 HBVDNA (IU/mL) | 7.27 (3.21) | 6.13 (1.60) | | <0.001 | | BCP mutation | A1762T/G1764A 16.56% ()
G1896A 16.56% ()
A1762T/G1764A/G1896A 2.55% ()
Others 3.50% ()
Not detected 60.83% () | A1762T/G1764A 41.18% ()
G1896A 5.88% ()
A1762T/G1764A/G1896A 5.88% ()
Not detected 41.18% () | Fisher | 0.02899 | | Fibroscan (Kpa) | 8.00 (6.20) | 10.45 (5.18) | | 0.012 |
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