Effect of Naringenin, Quercetin, and Sesamin on Xenobiotica-Metabolizing CYP1A and CYP3A in Mice Offspring after Maternal Exposure to Persistent Organic Pollutants

Figure 1

In vitro inhibition of CYP1A by quercetin, naringenin, and sesamin in the microsomes from mice exposed to different levels of POPs ( mice per group). CYP1A activity was measured by the rate of 7-ethoxyresorufin O-deethylation. Data are presented as the mean percentage of remaining activity and standard error of the enzyme activity in 6 mice.