Effect of Naringenin, Quercetin, and Sesamin on Xenobiotica-Metabolizing CYP1A and CYP3A in Mice Offspring after Maternal Exposure to Persistent Organic Pollutants

Figure 3

In vitro inhibition of CYP3A by quercetin, naringenin, and sesamin in hepatic microsomes from mice exposed to different levels of POPs ( mice per group). CYP3A activity was measured by the rate of 7-benzyloxyresorufin O-debenzylation. Data are presented as the mean percentage of remaining activity and standard error of the enzyme activity in 6 mice.