Laryngeal Rosai-Dorfman Disease (Sinus Histiocytosis with Massive Lymphadenopathy): A Retrospective Study of 5 Cases

Table 3

The course of treatment and relevant efficacy for the 5 RDD cases with laryngeal involvement.

Case number	Follow-up; (months)	Systemic regimen	Laryngeal treatment strategy	Condition of laryngeal lesions	Outcome
1	384	Prednisone 20 mg × 4 W	Open surgery + tracheotomy	Stable	AWD
2	165	Prednisone 30 mg × 2 W	Open surgery + tracheotomy	Stable	AWD/LFU
3	101	Prednisone 30 mg × 2 W + cladribine 50 mg × 1 W	Endosurgery ×2 + tracheotomy	Slow progress	AWD
4	98	Prednisone 30 mg × 2 W	Endosurgery ×2	Stable	AWD
5	8	Prednisone 30 mg × 2 W	Endosurgery + tracheotomy	Relieved	AWD

Note: AWD, alive with disease; LFU, lost to follow-up.