Effects of Aspirin and Intrauterine Balloon on Endometrial Repair and Reproductive Prognosis in Patients with Severe Intrauterine Adhesion: A Prospective Cohort Study

Table 3

Measures taken for prevention of postoperative severe IUA and parameters used for evaluation of severe IUA (literature review).

Study and year

Patient number

Antiadhesion therapy

EM (mm)

RM number

RIUAs number

LB number

P number

M number

IUD

Balloon

Aspirin

HRT

Other

Chen 1997

7

Y

N

N

Y

Tents

NR

7

NR

2

3

1

Fernandez 2006

71

N

N

N

Y

N

NR

69

56

21

28

7

Amer 2010

45

N

Y

N

Y

Amnion

NR

35

NR

4

10

6

Myers 2012

12

Y

Y

N

N

N

2–8

12

NR

4

6

2

Chen 2013

36

Y

N

N

Y

N

NR

NR

NR

NR

NR

NR

Tsui 2014

4

N

Y

N

Y

Gel

6–9

NR

NR

2

4

2

Mohamed 2015

40

N

Y

N

N

Amnion

NR

15

NR

NR

NR

NR

N: use; Y: no use; NR: not reported/unknown; HRT: hormone replacement therapy; EM: endometrial thickness; IUA: intrauterine adhesion; IUD: intrauterine device; RM: resumption of menses; RIUAs: recurrence of IUAs; LBN: live birth; P: pregnancy; M: miscarriage.