Microarray Analysis and Detection of MicroRNAs Associated with Chronic Thromboembolic Pulmonary Hypertension
Table 5
Functional enrichment analysis of the target genes of the key miRNAs.
Term
Description
Count
value
Upregulated
GO:0060736
Prostate gland growth
3
GO:0006366
Transcription from RNA polymerase II promoter
10
GO:0045893
Positive regulation of transcription, DNA-templated
10
GO:0060749
Mammary gland alveolus development
3
GO:0018105
Peptidyl-serine phosphorylation
5
hsa05205
Proteoglycans in cancer
7
hsa04310
Wnt signaling pathway
6
hsa04012
ErbB signaling pathway
5
hsa05200
Pathways in cancer
9
hsa04916
Melanogenesis
5
Downregulated
GO:0010557
Positive regulation of macromolecule biosynthetic process
10
GO:0006820
Anion transport
5
GO:0048666
Neuron development
7
GO:0031328
Positive regulation of cellular biosynthetic process
10
GO:0030278
Regulation of ossification
4
hsa04020
Calcium signaling pathway
5
Term represents the identification number of GO-BP or KEGG pathway. Description represents the name of the GO-BP or KEGG pathway. Counts represent the number of genes enriched in the GO-BP or KEGG pathway.