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BioMed Research International
Volume 2017 (2017), Article ID 8542576, 11 pages
https://doi.org/10.1155/2017/8542576
Review Article

A Systematic Review and Meta-Analysis on the Treatment of Cerebral Hemorrhage with NaoXueShu Oral Liquid

1Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Key Office of Encephalopathy TCM Research, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, China
2Weishi Hospital of Traditional Chinese Medicine, Henan 475500, China
3Beijing University of Chinese Medicine, Beijing 100029, China
4Guang An Men Hospital, China Academy of Chinese Medical Science, Beijing 100053, China

Correspondence should be addressed to Yonghong Gao; moc.liamtoh@8807hyoag and Hongcai Shang; moc.621@iacgnohgnahs

Received 13 February 2017; Accepted 16 April 2017; Published 29 May 2017

Academic Editor: Alexander N. Orekhov

Copyright © 2017 Lijun Wu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. Klebe, D. McBride, J. J. Flores, J. H. Zhang, and J. Tang, “Modulating the immune response towards a neuroregenerative peri-injury milieu after cerebral hemorrhage,” Journal of Neuroimmune Pharmacology, vol. 10, no. 4, pp. 576–586, 2015. View at Publisher · View at Google Scholar · View at Scopus
  2. C. Chen, L. X. Yuan, and G. M. Zhang, “Clinical application and experimental research progress of nao-xue-shu oral liquid in cerebrovascular disease,” Chinese Journal of Integrated Traditional Chinese and Western Medicine, vol. 12, no. 8, pp. 1005-1006, 2014. View at Google Scholar
  3. D. K. Wang, H. Y. Zhang, H. Y. Liu et al., “Analyses on stereology of mitochondrion of neurons that surround intracerebral hemorrhage in rats and the neuroprotective effect of astragalus injection for intracerebral hemorrhage,” Chinese Journal of Clinical Anatomy, vol. 31, no. 6, pp. 692–695, 2013. View at Google Scholar
  4. H. Y. Liu, Z. Sun, D. K. Wang et al., “The inhibition of astragalus and salviae miltiorrhizae injection on the neuronal apoptosis of the penumbra around the intracerebral hemorrhage in rats,” Lishizhen Medicine and Materia Medica Research, vol. 23, no. 8, pp. 1892–1895, 2012. View at Google Scholar
  5. J. Cai, R. Pan, X. Jia et al., “The combination of astragalus membranaceus and ligustrazine ameliorates micro-haemorrhage by maintaining blood-brain barrier integrity in cerebrally ischaemic rats,” Journal of Ethnopharmacology, no. 158, pp. 301–309, 2014. View at Publisher · View at Google Scholar · View at Scopus
  6. K. M. Li, G. Zhang, and J. B. Wu, “Overview of pharmacological research of leech,” Traditional Chinese Medicine Research, vol. 20, no. 2, pp. 62–64, 2007. View at Google Scholar
  7. Y. Zhang, J. C. Feng, J. Wu et al., “Protective effects of hirudin on acute experimental intracerebral hemorrhage,” China Journal of Chinese Materia Medica, vol. 31, no. 1, pp. 69–72, 2006. View at Google Scholar
  8. H. Dong, J. X. Ren, J. J. Wang et al., “Chinese medicinal leech: ethnopharmacology, phytochemistry, and pharmacological activities,” Evidence-Based Complementary and Alternative Medicine, vol. 2016, Article ID 7895935, 11 pages, 2016. View at Publisher · View at Google Scholar
  9. X. Ai and C. Liu, “Effect of nao-xue-shu oral liquid on the volume of hematoma in rats with cerebral hemorrhage and the protective effect of nerve function,” Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease, vol. 12, no. 7, pp. 859–861, 2014. View at Google Scholar
  10. L. Sun, Y. B. Liu, L. Wang et al., “Effect of Astragalus Injection on expression of BDNF in cerebral ischemia reperfusion injury in rats,” World Chinese Medicine, vol. 11, no. 4, pp. 686–689, 2016. View at Google Scholar
  11. B. Chen, X. Y. Miao, and W. Shi, “Effect of Naoxueshu on the expression of esopageal cancer related gene 4 in choroid plexus epithelial cells in intracerebral hemorrhage rats,” China Medicine, vol. 11, no. 11, pp. 1713–1717, 2016. View at Google Scholar
  12. Y. Hu, Y. H. Zhang, and C. X. Liu, “Effects of Nao-Xue-Shu oral liquid on cerebral function and apoptosis of peripheral penumbra after intracerebral hemorrhage in rats,” Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease, vol. 14, no. 15, pp. 1735–1737, 2016. View at Google Scholar
  13. X. Ai and C. Liu, “Neuroprotective effects of Nao-Xue-Shu oral liquid on acute cerebral infarction in rats,” Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease, vol. 13, no. 11, pp. 1278–1280, 2015. View at Google Scholar
  14. P. Adamczyk, S. He, A. P. Amar, and W. J. Mack, “Medical management of cerebral vasospasm following aneurysmal subarachnoid hemorrhage: a review of current and emerging therapeutic interventions,” Neurology Research International, vol. 2013, Article ID 462491, 10 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  15. G. Grasso, C. Alafaci, R. L. Macdonald et al., “Management of aneurysmal subarachnoid hemorrhage: state of the art and future perspectives,” Surgical Neurol Internation, no. 8, p. 11, 2017. View at Google Scholar
  16. X. G. Wang and X. Q. Zhao, “Paired study on the treatment of acute cerebral hemorrhage with nao-xue-shu oral liquid,” Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease, vol. 13, no. 7, pp. 937-938, 2015. View at Google Scholar
  17. S. J. Chen, H. Y. Wang, Y. Zuo et al., “Clinical observation on the treatment of secondary brain damage after intracerebral hemorrhage by Nao-Xue-Shu oral liquid,” Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease, vol. 14, no. 2, pp. 199–202, 2016. View at Google Scholar
  18. M. Z. Wang, L. Zhang, W. F. Jiang et al., “Clinical observation of nourishing qi, resolving stagnation, cooling blood and eliminating phlegm method in treating aphasia of mixed stroke,” Journal of Shanghai University of Traditional Chinese Medicine, vol. 29, no. 3, pp. 23–26, 2015. View at Google Scholar
  19. Y. Yan, M. Wang, L. Zhang et al., “Nao-Xue-Shu oral liquid improves aphasia of mixed stroke,” Evidence-Based Complementary and Alternative Medicine, vol. 2015, Article ID 709568, 6 pages, 2015. View at Publisher · View at Google Scholar
  20. X. W. Zhou, Y. Zuo, S. J. Chen et al., “Observation of clinical effect of nao-xue-shu oral liquid on patients with basal ganglia hemorrhage,” Shaanxi Medical Journal, vol. 44, no. 7, pp. 866-867, 2015. View at Google Scholar
  21. Y. Q. Yang and T. Xue, “Clinical study on naoxueshu oral liquid combined with nimodipine in treatment of hypertensive cerebral hemorrhage,” Drugs & Clinic, vol. 30, no. 11, pp. 1341–1344, 2015. View at Google Scholar
  22. H. Jiang, Y. Qin, T. Liu et al., “Nao-xue-shu oral liquid protects and improves secondary brain insults of hypertensive cerebral hemorrhage,” Evidence-Based Complementary and Alternative Medicine, vol. 2016, Article ID 9121843, 6 pages, 2016. View at Publisher · View at Google Scholar · View at Scopus
  23. Y. Yuan and D. Yuan, “HuoxueYiqi huatan qingre treatment of hemorrhagic stroke clinical research,” Chinese Journal of Aesthetic Medicine, vol. 21, no. 9, pp. 189-190, 2012. View at Google Scholar
  24. S. X. Wang, R. X. Song, Z. Wang et al., “Evaluation of clinical effect of naoxueshu oral liquid on hematoma absorption,” Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease, vol. 12, no. 4, pp. 452-453, 2014. View at Google Scholar
  25. D. Z. Xie, B. Y. Xu, Y. Sun et al., “Naoxueshu Liquid for Hemorrhagic Stroke,” Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease Journal, vol. 5, no. 8, pp. 690-691, 2007. View at Google Scholar
  26. W. C. Miao and R. Yan, “Clinical observation on the treatment of hypertensive cerebral hemorrhage with naoxueshu oral liquid,” Chinese Journal of Practical Nervous Diseases, vol. 17, no. 14, pp. 102-103, 2014. View at Google Scholar
  27. M. Lu, R. P. Xie, and Y. Fu, “Effect of naoxueshu oral liquid on cerebral hemorrhage caused by hypertension,” Chinese Journal of Rehabilitation Theory and Practice, vol. 10, no. 5, pp. 304-305, 2004. View at Google Scholar
  28. Y. Y. Gu and Y. Ma, “Naoxueshu oral liquid for the treatment of cerebral hemorrhage in 32 cases,” Henan Traditional Chinese Medicine, vol. 30, no. 10, pp. 982-983, 2010. View at Google Scholar
  29. Z. Y. Wang and Z. C. Ding, “Application of huoxue yiqi huatan tongluo treatment of cerebral hemorrhage in patients with clinical observation,” Contemporary Medicine Forum, vol. 12, p. 8, 2014. View at Google Scholar
  30. H. Wang, X. Z. Niu, and T. S. Su, “Clinical observation on the treatment of cerebral hemorrhage in convalescent stage with acupuncture combined with naoxueshu oral liquid,” World Latest Medicine Information, vol. 16, no. 3, pp. 110-111, 2016. View at Google Scholar
  31. S. H. Li, X. H. Han, G. Y. Jiang et al., “Clinical observation on the treatment of hypertensive cerebral hemorrhage with minimally invasive surgery of intracranial hematoma combined with naoxueshu oral liquid,” Chinese Journal of Practical Nervous Diseases, vol. 17, no. 17, pp. 82-83, 2014. View at Google Scholar
  32. C. Herweh, E. Jüttler, P. D. Schellinger et al., “Evidence against a perihemorrhagic penumbra provided by perfusion computed tomography,” Stroke, vol. 38, no. 11, pp. 2941–2947, 2007. View at Publisher · View at Google Scholar · View at Scopus
  33. H. B. Brouwers and J. N. Goldstein, “Therapeutic strategies in acute intracerebral hemorrhage,” Neurotherapeutics, vol. 9, no. 1, pp. 87–98, 2012. View at Publisher · View at Google Scholar · View at Scopus
  34. D. Wang, J. X. Zhai, Z. Y. Mou et al., “Discussing on the research of heterogeneity in meta-analysis,” Chinese Journal of Evidence-Based Medicine, vol. 9, no. 10, pp. 1115–1118, 2009. View at Google Scholar
  35. A. C. Alba, P. E. Alexander, J. Chang, J. Macisaac, S. Defry, and G. H. Guyatt, “High statistical heterogeneity is more frequent in meta-analysis of continuous than binary outcomes,” Journal of Clinical Epidemiology, vol. 70, pp. 129–135, 2016. View at Publisher · View at Google Scholar · View at Scopus