Research Article

In Vitro/In Silico Study on the Role of Doubling Time Heterogeneity among Primary Glioblastoma Cell Lines

Table 2

The computational parameters used to initialize the HDC model.

ParameterValue

Domain length, 5 mm (methods-computational domain)
Cell (& lattice) size, 14–20 μm (methods-computational domain)
Iteration time, 8 h (methods-computational domain [49])
Oxygen consumption, 6.25 10−17 M cell−1 s−1 (methods-computational domain [29])
Maximum oxygen, 6.7 10−6 M O2 cm−3 (methods-continuous compartment [29])
Oxygen decay rate, 0.0125 (ND) (methods-continuous compartment [29, 30, 58])