An ECM-Mimicking, Mesenchymal Stem Cell-Embedded Hybrid Scaffold for Bone Regeneration

Figure 11

Bone tissue formation in MSC-embedded hybrid scaffolds. Subcutaneously implanted MSC-seeded hybrid scaffolds were extracted 8 weeks after implantation and histological sections were prepared and stained with H&E stains. Four sections of different fields demonstrate the newly formed bone tissue (yellow arrows), blood vessels (red arrow), connective tissue (orange arrow), and Pro Osteon particle positions before demineralization (purple arrow).