An ECM-Mimicking, Mesenchymal Stem Cell-Embedded Hybrid Scaffold for Bone Regeneration

Figure 7

H&E staining of MSC-embedded hybrid scaffolds. MSC-embedded hybrid scaffolds were cultured in inductive medium for 7 days. Then, they were fixed, demineralized, and embedded in paraffin, and histological sections were stained with H&E. MSCs were extensively expanded within the hybrid scaffold: (a) ×40 and (b) ×400. PCL fibers and cell nuclei are indicated by yellow and blue arrows, respectively. Pro Osteon® particle positions before demineralization are bordered with green line and indicated with green arrows.

(a)

(b)