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BioMed Research International
Volume 2017 (2017), Article ID 8601027, 10 pages
Review Article

Study on Transformation of Ginsenosides in Different Methods

School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China

Correspondence should be addressed to Chun-chao Han and Xue-lan Zhang

Received 19 September 2017; Revised 6 November 2017; Accepted 20 November 2017; Published 14 December 2017

Academic Editor: Gail B. Mahady

Copyright © 2017 Meng-meng Zheng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Ginseng is a traditional Chinese medicine and has the extensive pharmacological activity. Ginsenosides are the major constituent in ginseng and have the unique biological activity and medicinal value. Ginsenosides have the good effects on antitumor, anti-inflammatory, antioxidative and inhibition of the cell apoptosis. Studies have showed that the major ginsenosides could be converted into rare ginsenosides, which played a significant role in exerting pharmacological activity. However, the contents of some rare ginsenosides are very little. So it is very important to find the effective way to translate the main ginsenosides to rare ginsenosides. In order to provide the theoretical foundation for the transformation of ginsenoside in vitro, in this paper, many methods of the transformation of ginsenoside were summarized, mainly including physical methods, chemical methods, and biotransformation methods.