Research Article
Heterogeneous Periostin Expression in Different Histological Variants of Papillary Thyroid Carcinoma
Table 1
PN expression in tumor epithelial cells and clinicopathological characteristics of PTC.
| Clinicopathologic features | Case number | PN | | OR (95% CI) | Low score | High score | # | % | # | % | # | % | value |
| Sex | | Female | | | | | | | | 0.69 (0.12–3.81) | Male | | | | | | |
| Age | | <45 | | | | | | | | 0.63 (0.18–2.20) | >45 | | | | | | |
| Tumor stage | | Stages I, II | | | | | | | | 0.89 (0.26–3.07) | Stages III, IV | | | | | | |
| Histologic subtype | | Conventional | | | | | | | | 10.86 (0.55–211.91) | Follicular | | | | | | | Macrofollicular | | | | | | | 1.4 (0.02–78.80) | Tall cells | | | | | | | 1.00 (0.24–4.13) | Oncocytic | | | | | | | 105.00 (3.73–2948.28) |
| Multifocality | | Yes | | | | | | | | 0.8 (0.20–3.08) | No | | | | | | |
| Tumor size | | <2.18 cm | | | | | | | | 0.90 (0.23–3.53) | >2.18 cm | | | | | | |
| Lymphovascular invasion | | Absent | | | | | | | | 0.33 (0.06–1.73) | Present | | | | | | |
| Lymph node metastasis | | Absent | | | | | | | | 1.03 (0.17–6.06) | Present | | | | | | |
| Extrathyroidal invasion | | Absent | | | | | | | | 0.83 (0.24–2.90) | Present | | | | | | |
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: chi-square test; OR: odd ratio; CI: confidence interval.
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