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BioMed Research International
Volume 2017 (2017), Article ID 8728017, 7 pages
Research Article

Insulin Resistance and Its Association with Metabolic Syndrome in Korean Children

1College of Sport Science, Sungkyunkwan University, Suwon, Republic of Korea
2Department of Sports Science, Korea Institute of Sport Science, Seoul, Republic of Korea
3Department of Civil Engineering, Sangmyung University, Cheonan, Republic of Korea

Correspondence should be addressed to Hyunsik Kang

Received 4 September 2017; Revised 21 November 2017; Accepted 3 December 2017; Published 31 December 2017

Academic Editor: Yoshifumi Saisho

Copyright © 2017 Jinkyung Cho et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. This study investigated the association between insulin resistance (IR) and metabolic syndrome (MetS) in children. Methods. A cross-sectional study involving 1036 healthy children aged between 7 and 13 years was conducted. Homeostasis model assessment of insulin resistance (HOMA-IR) was calculated as an index of IR. Participants were classified according to the HOMA-IR quartiles. Results. Incremental, linear trends were found in age (), body mass index (BMI) (), body fat (), waist circumference (), resting blood pressures (BP) (), triglycerides (TG) (), total cholesterol (TC) (), high density lipoprotein-cholesterol (HDL-C) (), FBG (), and insulin (<0.001) according to incremental HOMA-IR categories (from the 1st to 4th quartile). Compared with children in the 1st HOMA-IR quartile, children in the 4th HOMA-IR quartile had significantly higher odd ratios (ORs) of abnormalities in systolic () and diastolic BP (), FBG (), TG (), TC (), and HDL-C () even after adjustments for age, gender, BMI, and body fat percentage. Children in the 3rd HOMA-IR quartile had significant abnormalities in FBG (), TG (), and HDL-C () even after adjustments for the covariates. Conclusion. The current findings suggest that IR is significantly associated with the clustering of MetS risk factors in children in Korea.