Repair of Osteochondral Defects Using Human Umbilical Cord Wharton’s Jelly-Derived Mesenchymal Stem Cells in a Rabbit Model

Figure 4

Gross and histological scores for repaired tissues in rabbit cartilage defects. (a) Gross score, the hWJMSCs-ECM and hWJMSC-Cs-ECM groups were significantly different () 3, 6, and 12 months after transplantation. Both the hWJMSCs-ECM and hWJMSC-Cs-ECM groups were significantly different from the untreated and scaffold alone groups (). (b) ICRS histological score, the hWJMSCs-ECM and hWJMSC-Cs-ECM groups were significantly different () 3, 6, and 12 months after transplantation. Both the hWJMSCs-ECM and hWJMSC-Cs-ECM groups were significantly different from the untreated and scaffold alone groups (), except the hWJMSC-Cs-ECM group at 12 months.

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