Tissue Factor Pathway Inhibitor-1 Is a Valuable Marker for the Prediction of Deep Venous Thrombosis and Tumor Metastasis in Patients with Lung Cancer
Table 2
The biological and clinical parameters of controls and patients with NSCLC.
Variables
NSCLC patients
Disease controls
Healthy controls
value
Number of subjects
188
112
130
Age (years)
45.2 ± 12.3
47.1 ± 11.4
47.9 ± 13.2
>0.05
Sex (M/F)
118/70
61/51
72/58
>0.05
BMI (kg/m2)
25.3 ± 2.7
26.1 ± 3.0
25.5 ± 2.7
>0.05
Smoking subjects (M/F)
94/17
45/15
60/17
>0.05
SBP (mmHg)
130 ± 15
132 ± 14
133 ± 12
>0.05
DBP (mmHg)
82 ± 10
80 ± 11
79 ± 12
>0.05
Glu (mmol/L)
5.12 ± 1.55
5.30 ± 1.69
5.25 ± 1.77
>0.05
WBC (109/L)
6.17 ± 2.22
5.74 ± 3.01
5.42 ± 2.15
>0.05
PLT (109/L)
190.1 ± 21.5
199.3 ± 18.0
210.1 ± 20.1
>0.05
CRP (mg/L)
5.5 (0.5–19.5)
4.5 (0.5–14.6)
2.4 (0.5–7.6)
<0.05
PT (seconds)
11.0 ± 3.1
11.6 ± 2.6
11.7 ± 2.2
>0.05
aPTT (seconds)
24.1 ± 5.0
25.8 ± 3.9
26.0 ± 3.8
>0.05
Fbg (g/L)
3.35 ± 1.20
2.68 ± 1.30
2.54 ± 2.01
<0.01
D-D (mg/L)
0.65 ± 0.14
0.42 ± 0.10
0.26 ± 0.04
<0.01
FVIII:C (%)
107.5 ± 12.3
95.1 ± 11.2
91.2 ± 13.0
<0.05
AT (%)
77.0 ± 10.1
92.4 ± 10.8
98.5 ± 13.1
<0.01
TFPI-1 (ng/ml)
51.0 ± 8.6
79.2 ± 13.2
87.1 ± 15.9
<0.01
Data are presented as mean ± SD, and CRP is expressed with median and range. NSCLC: non-small cell lung cancer. BMI: body mass index. SBP: systolic blood pressure. DBP: diastolic blood pressure. GLU: serum glucose. WBC: white blood cell count. PLT: platelet count. CRP: C- reactive protein. PT: prothrombin time. aPTT: activated partial thromboplastin time. Fbg: fibrinogen. D-D: d-dimer. FVIII:C: coagulating factor VIII procoagulant activity. AT: antithrombin. TFPI-1: tissue factor pathway inhibitor-1. value: compared among three groups. : compared with disease controls and healthy controls. : compared with healthy controls.
