Closer to a Uniform Language in Colposcopy: Study on the Potential Application of 2011 International Federation for Cervical Pathology and Colposcopy Terminology in Clinical Practice

Table 2

Correlation of colposcopic findings in 2011 IFCPC nomenclature with histological diagnoses and their PPVs.

Colposcopic finding	Histological diagnoses (N)				Total (%)	PPV (%)
	Normal or benign	LSIL	HSIL	Carcinoma		LSIL+; (95% CI)	HSIL+; (95% CI)
Minor changes
Thin	121	89	53	0	263	54.0%	20.2%
	(46.0)	(33.8)	(20.2)	(0.0)	(100.0)	(47.9%–60.1%)	(15.3%–25.0%)
Fine mosaic	3	12	10	0	25	88.0%	40.0%
	(12.0)	(48.0)	(40.0)	(0.0)	(100.0)	(74.3%–100%)	(19.4%–60.6%)
Fine punctuation	10	11	10	0	31	67.7%	32.3%
	(32.3%)	(35.5)	(32.3)	(0.0)	(100.0)	(50.3%–85.2%)	(14.8%–49.7%)
Major changes
Dense	9	8	43	3	63	85.7%	73.0%
	(14.3)	(12.7)	(68.3)	(4.8)	(100.0)	(76.8%–94.6%)	(61.7%–84.3%)
Coarse mosaic	3	3	18	2	26	88.5%	76.9%
	(11.5)	(11.5)	(69.2)	(7.7)	(100.0)	(75.3%–100%)	(59.6%–94.3%)
Coarse punctuation	3	3	10	1	17	82.4%	64.7%
	(17.6)	(17.6)	(58.8)	(5.9)	(100.0)	(62.1%–100%)	(39.4%–90.0%)
Sharp border	3	3	5	2	13	76.9%	53.8%
	(23.1)	(23.1)	(38.5)	(15.4)	(100.0)	(50.4%–100%)	(22.5%–85.2%)
Inner border sign	0	0	4	0	4	100.0%	100.0%
	(0.0)	(0.0)	(100.0)	(0.0)	(100.0)
Ridge sign	0	0	5	2	7	100.0%	100.0%
	(0.0)	(0.0)	(71.4)	(28.6)	(100.0)
Nonspecific
Iodine negativity	167	104	71	2	344	51.5%	21.2%
	(48.5)	(30.2)	(20.6)	(5.8)	(100.0)	(46.1%–56.8%)	(16.9%–25.6%)
Suspicious for invasion
Atypical vessels	0	0	4	4	8	100.0%	100.0%
	(0.0)	(0.0)	(50.0)	(50.0)	(100.0)
Additional signs	0	0	1	2	3	100.0%	100.0%
	(0.0)	(0.0)	(33.3)	(66.7)	(100.0)
Miscellaneous
Condyloma	0	11	0	0	11	100.0%	0.0%
	(0.0)	(100.0)	(0.0)	(0.0)	(100.0)
Polyp	20	6	5	0	31	35.5%	16.1%
	(64.5)	(19.4)	(16.1)	(0.0)	(100.0)	(17.6%–53.3%)	(2.4%–29.8%)
Contact bleeding	5	1	1	1	8	37.5%	25.0%
	(62.5)	(12.5)	(12.5)	(12.5)	(100.0)	(0.0%–80.8%)	(0.0%–63.7%)
Total	344	251	240	19	854	—	—
	(40.3)	(29.4)	(28.1)	(2.2)	(100.0)

: acetowhite epithelium.