Idiosyncratic Drug-Induced Liver Injury (IDILI): Potential Mechanisms and Predictive Assays

Figure 2

Mechanisms of mediating ROS within the liver. Abbreviations are used as follows: superoxide dismutase (SOD), catalase (CAT), peroxiredoxin (Prx), thioredoxin (Trx), thioredoxin reductase (TrxR), glutathione peroxidase (GPx), glutathione (GSH), and glutathione disulfide (GSSG).