Serum Sclerostin Levels in Patients with Ankylosing Spondylitis and Rheumatoid Arthritis: A Systematic Review and Meta-Analysis

Table 1

Characteristics of included studies in the present meta-analysis.

				Case				Control
References	Year	Region	Study type		Sex (M/F)	Mean (pg/ml)/(pmol/L)	SD (pg/ml)/(pmol/L)		Sex (M/F)	Mean (pg/ml)/(pmol/L)	SD (pg/ml)/(pmol/L)		Criteria for diseases	Source for control	Measurement	Quality score
Saad et al. [12]	2012	Brazil	Case-control	30	24/6	60.5	32.7	30	24/6	96.7	52.9	0.002	New York (1984)	Hospital	ELISA	6
Sakellariou et al. [13]	2016	Greece	Cross-sectional	57	53/4	357.4	280.85	34	32/2	276.4	103.79	0.611	New York (1984)	NA	ELISA	7
Appel et al. [14]	2009	German	Case-control	46	30/16	240.78	1078.35	50	33/17	522.26	1100.3	<0.01	NA	NA	ELISA	7
Korkosz et al. [9]	2013	Poland	Cross-sectional	78		290	639.4	23		120	431.62	0.09	New York (1984)	NA	ELISA	6
Rossini et al. [15]	2016	Italy	Case-control	71	59/12	25.2	79.21	71	59/12	38	144.93	<0.01	New York (1984)	Hospital	ELISA	8
Tuylu et al. [16]	2014	Turkey	Case-control	94	65/29	137.97	113.88	68	48/20	151	158	0.6	New York (1984)	NA	ELISA	6
Ustun et al. [17]	2014	Turkey	Cross-sectional	44	34/10	427.69	368.1	41	31/10	656.32	643.51	0.037	New York (1984)	NA	ELISA	7
Paccou et al. [18]	2014	France	Cross-sectional	75	19/56	440	190	75	19/56	450	200	0.96	ACR (2010)	Hospital	ELISA	8
Mehaney et al. [19]	2015	Egypt	Cross-sectional	40	28/12	400	200	40	28/12	500	200	0.14	ACR (2010)	Hospital	ELISA	8
Świerkot et al. [20]	2015	Poland	Clinical study	30	30/0	400	260	12	12/0	350	170	>0.05	ACR (1987)	NA	ELISA	—

NA: not available; SD: standard deviation.