Clinical Features and Outcome in Adult Cases of Tuberculous Meningitis in Tertiary Care Hospital in Antananarivo, Madagascar

Table 2

Univariate analysis of variables associated with inpatient mortality in TBM.

Variable	Survived	Died	value
	(%)	(%)
	54 (72.0)	21 (28.0)
Age ≥ 35 years	22 (40.7)	14 (66.7)	0.044
Male gender	28 (51.8)	14 (66.7)	0.246
HIV infected	2 (3.7)	1 (4.8)	0.633
Symptoms prior to admission ≥ 4 weeks	24 (44.4)	12 (57.1)	0.323
Time to diagnosis ≥ 7 days	18 (33.3)	6 (28.6)	0.691
BCG vaccination	11 (20.4)	1 (4.8)	0.090
TB history	3 (5.6)	2 (9.5)	0.432
Weight loss	21 (38.9)	12 (57.1)	0.153
Cough ≥ 2 weeks	16 (29.6)	6 (28.6)	0.928
Photophobia	5 (9.3)	2 (9.5)	0.972
Seizures	16 (29.6)	3 (14.3)	0.140
Neck stiffness	37 (68.5)	15 (71.4)	0.806
Altered consciousness	41 (75.9)	14 (66.7)	0.416
Coma	2 (3.7)	4 (19.1)	0.048
Cranial nerve palsy	11 (20.4)	2 (9.5)	0.224
Focal neurological signs	6 (11.1)	2 (9.5)	0.604
CSF WCC ≥ 150 per mm^3	16 (29.6)	11 (52.4)	0.065
CSF glucose level ≥ 1.1 mmol/L	37 (69.8)	11 (52.4)	0.157
CSF protein level ≥ 1 g/L	31 (58.5)	16 (76.2)	0.154
Active pulmonary TB	5 (9.3)	4 (19.1)	0.241