Research Article

Lesion Pattern, Mechanisms, and Long-Term Prognosis in Patients with Monoparetic Stroke: A Comparison with Nonmonoparetic Stroke

Table 1

Comparison of clinical features between monoparetic and nonmonoparetic stroke patients at admission: number (%), mean ± SD.

Nonmonoparetic stroke 
= 555
Monoparetic stroke 
= 31

Age67.5 ± 13.768.8 ± 11.80.611
Female260 (46.8)13 (41.9)0.594
Hypertension371 (66.8)23 (74.2)0.396
Diabetes164 (29.5)12 (38.7)0.279
Hyperlipidemia287 (51.7)21 (67.7)0.082
Current smoking150 (27.0)8 (25.8)0.882
Previous stroke85 (15.3)2 (6.5)0.177
Ischemic heart disease115 (20.7)10 (32.3)0.127
Atrial fibrillation192 (34.6)9 (29.0)0.525
Valvular heat disease113 (20.4)5 (16.1)0.568
Alcohol92 (16.6)3 (9.7)0.310
Previous medication
 Antiplatelet221 (39.8)15 (48.4)0.344
 Anticoagulant80 (14.4)6 (19.4)0.449
 Statin145 (26.1)16 (51.6)0.002
Stenosis286 (51.5)14 (45.2)0.490
Stenosis pattern0.620
 Intracranial and extracranial82 (14.8)3 (9.7)
 Intracranial only157 (28.3)7 (22.6)
 Extracranial only47 (8.5)4 (12.9)
 No stenosis269 (48.5)17 (54.8)
TOAST classification0.505
 Large artery atherosclerosis128 (23.1)9 (29.0)
 Lacune85 (15.3)3 (9.7)
 Cardioembolism207 (37.3)12 (38.7)
 Two or more92 (16.6)3 (9.7)
 Cryptogenic35 (6.3)4 (12.9)
 Other causes8 (1.4)0 (0)
Nonlacunar470 (84.7)28 (90.3)0.392
Initial NIHSS6.6 ± 7.91.3 ± 1.0<0.001
Poor outcome191 (34.4)2 (6.5)0.001

NIHSS: the National Institutes of Health Stroke Scale. Poor outcomes indicate modified Rankin scale ≥3 at 3 months.