Enhancement of Angiogenesis by Ultrasound-Targeted Microbubble Destruction Combined with Nuclear Localization Signaling Peptides in Canine Myocardial Infarction

Figure 7

Pathomorphology of infarcted myocardium after Ang-1 gene transfection. Pathological specimens of the left ventricular short axis at the papillary muscle level from all groups on day 28 after Ang-1 transfection in canines. The tissue in white (marked by black arrow) indicated infarcted myocardial, and the tissue in red represented the noninfarcted myocardium. A wide range of tissue in white indicated more MI area in (a), whereas a higher percentage of tissue in red indicated noninfarcted myocardium in (c). (a), (b), (c), (d), and (e) represented groups A, B, C, D, and E, respectively.

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