Research Article

Enhancement of Angiogenesis by Ultrasound-Targeted Microbubble Destruction Combined with Nuclear Localization Signaling Peptides in Canine Myocardial Infarction

Table 1

Cardiac function in each group 28 days after treatment .

GroupsLVEDD (mm)LVESD (mm)LVEDV (ml)LVESV (ml)LVEF (%)
Baseline28 dBaseline28 dBaseline28 dBaseline28 dBaseline28 d

Group A27.1 ±  29.3 ±  25.3 ± 1.729.6 ± 9.433.2 ±  18.4 ± 5.723.1 ± 4.138.0 ± 2.429.7 ±  
Group B28.9 ±  1.231.0 ±  24.0 ±  1.224.7 ±  32.0 ± 3.237.6 ±  20.0 ± 2.322.0 ±  37.6 ± 2.641.6 ±  
Group C30.9 ±  33.4 ±  25.3 ±  1.726.0 ±  37.3 ± 4.545.0 ±  23.1 ± 3.923.6 ±  37.3 ± 3.146.9 ±  
Group D28.3 ±  29.3 ±  23.6 ± 1.723.7 ±  30.7 ± 6.333.4 ±  19.3 ± 3.819.9 ±  36.8 ± 3.640.4 ±  
Group E29.9 ±  31.0 ±  24.9 ± 1.926.6 ±  34.9 ± 6.237.8 ±  22.0 ± 4.126.1 ±  36.9 ± 3.133.6 ±  
2.9595.0402.6004.0651.664.9321.5803.2920.10733.173
0.0360.0030.0560.0090.1620.0040.2050.0240.9790.000

LVEF = left ventricular eject fraction, LVEDD = left ventricular end-diastolic dimension, LVESD = left ventricular end-systolic dimension, LVEDV = left ventricular end-diastolic volume, and ESV = left ventricular end-systolic volume. Values are means ± SD. , compared with group A; , compared with group B; , compared with group C; , compared with group D; and , compared with group E.