Research Article

Evidence of Immunosuppressive and Th2 Immune Polarizing Effects of Antidiabetic Momordica charantia Fruit Juice

Table 2

Ratios of Th1 and Th2 cytokine concentrations in cell culture supernatants.

Leafy stem Fruit
Total juice
(100 μg/ml)
Filtered juice
(100 μg/ml)
Total juice
(100 μg/ml)
Filtered juice
(100 μg/ml)
IFN-γ/IL4 IFN-γ/IL-4

Ratios of cytokines from cells without mitogen11.121.050.5516.19
Ratios of cytokines from cell with mitogen (PHA) stimulation

The values are ratios of cytokine concentrations in supernatants of unstimulated and PHA-stimulated cells cultured in presence of 100 g/ml of plant juices. Cytokine concentrations are determined as described in Materials and Methods. < 0.05 indicates significant difference between both ratios with mitogen and without mitogen stimulation.