Research Article

Cell Signaling Pathway in 12-O-Tetradecanoylphorbol-13-acetate-Induced LCN2 Gene Transcription in Esophageal Squamous Cell Carcinoma

Figure 8

Schematic presentation of proposed signal pathway for regulating LCN2 gene expression in esophageal carcinoma cells. Xs, transcription factors bound to TPA-responsive element, such as MISP, KLF10, KLF15, PPP1R18, and RXRβ. TRE, TPA-responsive element.