Role of MicroRNA-103a Targeting ADAM10 in Abdominal Aortic Aneurysm

Figure 1

ADAM10 was upregulated in murine AAA. Western blot analysis of (a) ADAM10 (control, ; AngII, ; p, 0.000); (b) ADAM17 (control, ; AngII, ; p, 0.000); (c) ADAM9 (control, ; AngII, ; p, 0.000); and (d) ADAM12 on day 21 of Ang II infusion (control, ; AngII, ; p, 0.0047). GAPDH is the reference protein. , , control group, , and Ang II group, . (e) Examples of IHC staining of ADAM10 in Ang II induced AAA and control aorta (scale bar 10 μm) (control, ; AngII, ; p, 0.033), control group, , and Ang II group, ; (f) ADAM10 gene expression determined by qRT-PCR (control, ; AngII, ; ), control group, , and Ang II group, .

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