Role of MicroRNA-103a Targeting ADAM10 in Abdominal Aortic Aneurysm

Figure 5

Temporal expression of ADAM10 and miR-103a/107 in AngII induced murine AAA. Control group, ; AngII 7 d group, ; AngII 14 d group, ; AngII 28 d group, . (a), miR103a-3p expression determined by qRT-PCR (control, ; 7 d, ; 14 d, ; 28 d, ; p, 7 d/control, 0.029; 14 d/control, 0.000; 28 d/control, 0.006; 14 d/7 d, 0.014; 28 d/7 d, 0.099; 28 d/14 d, 0.055); (b), miR107-3p expression determined by qRT-PCR (control, ; 7 d, ; 14 d, ; 28 d, ; p, 7 d/control, 0.169; 14 d/control, 0.000; 28 d/control, 0.125; 14 d/7 d, 0.950; 28 d/7 d, 0.293; 28 d/14 d, 0.099); (c) ADAM10 protein expression shown by Western blot analysis (control, ; 7 d, ; 14 d, ; 28 d, ; p, 7 d/control, 0.416; 14 d/control, 0.046; 28 d/control, 0.014; 14 d/7 d, 0.105; 28 d/7 d, 0.528; 28 d/14 d, 0.391). ; .

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