Research Article

Involvement of the PI3K/Akt/NF-κB Signaling Pathway in the Attenuation of Severe Acute Pancreatitis-Associated Acute Lung Injury by Sedum sarmentosum Bunge Extract

Table 1

Serum alanine transaminase (ALT) and serum creatinine (Scr) levels after administering SSBE at different time points.

0 h (control)3 h6 h12 h24 h

ALT (U/L)57.00 ± 2.5157.14 ± 1.9559.14 ± 9.1054.14 ± 6.5455.71 ± 7.32
Scr (μmol/L)37.29 ± 3.9935.43 ± 4.3137.86 ± 3.1336.14 ± 6.0437.14 ± 5.46

Seven male SD rats were used as control (SSBE was not administered). Twenty-eight male SD rats were given SSBE subcutaneously at a dose of 100 mg/kg every 12 h. Blood samples were also drawn from the control group (0 h group). Blood samples after SSBE administration were collected at 3 h, 6 h, 12 h, and 24 h after administration of SSBE.